Foundation Medicine, Inc. Bioinformatics Scientist II Bioinformatics Scientist II 400 Summer Street, Boston, Massachusetts, United States Full Time About the Job: The Bioinformatics Scientist II develops and supports clinical trial and companion diagnostics (CDx) biomarker strategy through advanced analytical and scientific contributions. This role applies bioinformatics and cancer biology expertise to contribute to biomarker rule development, analytical methods, and workflow components that support consistent, scalable clinical reporting. The incumbent provides scientific, technical, and directional contributions for designated projects on an interdisciplinary team focused on making a clinical impact through advanced analysis at large scale. The Bioinformatics Scientist II is also responsible for supporting novel biomarker and companion diagnostics development by mining and analyzing various types of data generated during the product development and validation process. Key Responsibilities: Partners within an interdisciplinary team of Bioinformatics Scientists, Biostatisticians, Laboratory Scientists, Regulatory experts, and other teams to support the development and implementation of biomarker strategy for clinical trials and CDx Contributes to biomarker implementation by supporting rule development and technical execution across studies Leads biomarker scoping for individual studies by evaluating feasibility of biomarker definitions, performing data analyses to inform decisions, and providing technical input in partner-facing scoping discussions Identifies opportunities to improve existing biomarker workflows and documentation, and provides technical input to enhance quality and efficiency Contributes to development, refinement, and consistent application of biomarker guidance across studies Contributes scientific input to biomarker strategy discussions and evaluates feasibility across studies Develops and executes analytical and validation approaches for biomarker analyses Executes analytical work in support of product development, including method development, feasibility assessment, and evaluation of biomarker applicability Provides technical input to biopharma partner-specific discussions related to biomarker analyses and implementation Provides technical input to regulatory documentation and participates in regulatory discussions related to biomarker analyses Contributes to biomarker inquiry support by independently resolving standard inquiries, performing analyses, and assisting with triage and documentation of incoming questions Contributes to and improves shared tools and datasets, ensuring they are accurate, reusable, and welldocumented Mentors Scientist I team members and supports team coordination and documentation needs Presents scientific and technical data to colleagues in a clear and cohesive manner Other duties as assigned Comply with FMI's attendance policies Qualifications: Basic Qualifications: Masters degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline 2+ years of relevant industry or academic experience Proficiency with scripting for data analysis using Python, R, or similar Preferred Qualifications: PhD degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline 3+ years of industry experience Strong scientific understanding of molecular biology and genomics Experience in cancer research, including a working understanding of computational approaches for cancer genome analysis Knowledge of predictive biomarkers for cancer therapy Knowledge of clinical trial and CDx biomarker strategy, processes, and requirements Knowledge and experience with Next-Generation Sequencing (NGS) Strong analytical skills with experience in genomic data analysis Demonstrated ability to work independently and contribute to team projects Ability to work in a multidisciplinary, fast-paced, dynamic, and results-oriented environment Understanding of HIPAA and the importance of patient data privacy Commitment to reflect FMIs values: Integrity, Courage, and Passion The expected salary range for this position based on the primary location of Boston, MA is $129,840 - $162,300 per year. The salary range is commensurate with Foundation Medicines compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for Foundation Medicine's benefits. #LI-Hybrid PI286551734 #J-18808-Ljbffr
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